AI Companies in United States

NVIDIA

Santa Clara

NVIDIA is the world leader in AI computing hardware and software. Creator of CUDA, cuDNN, and the dominant GPU platform for AI training and inference.

Apple AI

Cupertino

Apple AI focuses on the research and development of on-device artificial intelligence, primarily through its MLX framework – an Apple silicon-optimized toolkit for developing and deploying large language models. Targeting AI researchers and developers, MLX enables private, efficient LLM experimentation and deployment directly on Apple hardware, bypassing reliance on cloud infrastructure. This positions Apple AI as a provider of both foundational ML technology and a secure, localized AI development environment.

Microsoft AI

Redmond

Microsoft AI provides a comprehensive suite of artificial intelligence services and products, including the Copilot assistant and Azure AI platform. Leveraging large language models developed in partnership with OpenAI, they offer generative AI and cloud-based AI solutions for enterprise applications. Their focus is on enabling businesses to integrate AI capabilities for increased productivity, innovation, and sustainability initiatives.

Google Cloud AI

Mountain View

Google Cloud AI provides a comprehensive suite of cloud-based artificial intelligence services for enterprise customers. Their core offering, Vertex AI, is a unified platform enabling the full lifecycle of machine learning development – from model building and tuning to deployment and MLOps. Google Cloud AI differentiates itself through decades of internal AI research – including the development of transformer models – and a focus on enabling customizable, production-ready AI agents for business automation.

Google AI

Mountain View

and general knowledge: Google AI develops cutting-edge large language models like Gemini, alongside the widely-adopted TensorFlow machine learning framework and supporting infrastructure. Their key innovations center on multimodal AI – enabling models to process and understand text, images, audio, and video – as demonstrated by Gemini’s advanced reasoning and creative capabilities. Targeting developers, researchers, and general consumers, Google AI integrates these technologies across numerous Google products and recently launched the Gemini API for broader access and application development.

Amazon AI

Seattle

Amazon AI provides a comprehensive suite of cloud-based artificial intelligence services and infrastructure through AWS, including the development of foundation models like Titan and the SageMaker AI platform. Their core offering centers on enabling organizations to build, train, and deploy agentic AI applications at scale, leveraging specialized infrastructure and a robust data foundation. Targeting businesses across all industries, Amazon AI differentiates itself by offering end-to-end capabilities – from model development to data governance – with a focus on cost optimization and enterprise-grade security.

Tesla AI

Palo Alto

Tesla AI engineers end-to-end neural networks powering its Autopilot driver-assistance system and the development of its Full Self-Driving (FSD) capability, utilizing a massive fleet-collected dataset for training and validation. Key innovations include advanced computer vision based on video prediction and a data-centric approach to AI model improvement, exemplified by the recent move to fully convolutional networks for FSD. Beyond automotive applications, Tesla AI is developing Optimus, a general-purpose humanoid robot intended for automated tasks, leveraging similar AI infrastructure and computer vision techniques.

Salesforce AI

San Francisco

Salesforce AI delivers embedded artificial intelligence capabilities across the Salesforce Customer 360 platform, most notably through its Einstein GPT and Einstein Copilot offerings. Leveraging large language models and proprietary machine learning, Salesforce AI provides generative AI features like automated email generation, call summarization (via Sales AI), personalized marketing journeys, and AI-powered customer service tools like Agentforce – all integrated with CRM data. These solutions are targeted towards enterprise businesses seeking to enhance sales, service, marketing, and commerce operations, and have enabled features like automated knowledge base creation and the ability to integrate custom LLMs via the Einstein Trust Layer.

AMD

Santa Clara

AMD designs high-performance CPUs and GPUs, and through its Instinct accelerators and ROCm software is a major supplier of hardware for AI training and inference, competing with NVIDIA in the data-center market.

Adobe Sensei

San Jose

Adobe Sensei is the AI and machine learning engine powering Adobe’s suite of creative and digital experience tools. Its core technology centers on generative AI models like Firefly, enabling content creation, automation, and intelligent features within applications like Photoshop, Illustrator, and Experience Manager. Targeting creative professionals, marketers, and enterprise businesses, Sensei delivers enhanced productivity and personalized experiences through integrated AI capabilities.

IBM watsonx

Armonk

IBM watsonx is an enterprise AI platform offering foundation models – including open-source options – and governance tools designed to accelerate the deployment of generative AI. The platform focuses on enabling businesses to build, deploy, and monitor AI assistants and agents across hybrid cloud environments. watsonx targets large organizations seeking to integrate AI into core workflows while maintaining control, compliance, and data security.

ServiceNow AI

Santa Clara

ServiceNow AI develops AI-powered workflow automation solutions for large enterprises. Their core offering leverages generative AI and machine learning to automate tasks within existing ServiceNow platforms for IT service management, human resources, and customer service operations. This enables organizations to improve operational efficiency and employee/customer experiences by intelligently resolving issues and streamlining processes.

Intel

Santa Clara

Intel designs and manufactures CPUs and AI accelerators, including its Gaudi line for deep-learning training and inference and AI capabilities integrated across its Core and Xeon processors.

John Deere AI

Moline

John Deere AI develops intelligent solutions for agricultural and construction equipment, most notably its autonomous 8R and 9R tractor platforms and the See & Spray™ Ultimate technology. Utilizing computer vision and machine learning, See & Spray™ selectively identifies and targets weeds in-season, reducing herbicide use by up to 80%. These innovations are targeted towards large-scale agricultural operations seeking to improve efficiency, reduce input costs, and promote sustainable farming practices, and have earned John Deere recognition for its advancements in precision agriculture technology.

Airbnb

San Francisco

Airbnb is a hospitality platform connecting travelers with lodging and experience providers globally. The company leverages AI-powered algorithms for dynamic pricing, personalized search ranking, and robust fraud prevention to optimize both host revenue and guest satisfaction. Targeting leisure and business travelers, Airbnb differentiates itself through a vast inventory of unique accommodations and experiences unavailable through traditional hotel chains.

CrowdStrike

Austin

CrowdStrike is a U.S.-based cybersecurity firm specializing in endpoint and cloud workload protection. Their core offering is the Falcon platform, an AI-powered agentic security system that unifies threat prevention, detection, and response capabilities. CrowdStrike targets enterprises seeking comprehensive, AI-driven cybersecurity to proactively defend against increasingly sophisticated threats, particularly in the context of emerging AI technologies.

Snowflake

Bozeman

Snowflake provides a cloud-based data platform enabling organizations to store, process, and analyze data at scale. Their core offering, the AI Data Cloud, incorporates features like Cortex AI to facilitate the development and deployment of custom large language models (LLMs) directly within the platform. Snowflake targets data-intensive enterprises seeking to break down data silos and accelerate AI innovation without data movement or complex infrastructure management.

DoorDash

San Francisco

DoorDash is a leading on-demand food and goods delivery platform operating primarily in the United States. The company leverages machine learning models for real-time demand forecasting, efficient driver dispatch, and optimized route planning to minimize delivery times and costs. This technology serves both consumers seeking convenient delivery and merchants aiming to expand reach and streamline fulfillment, ultimately driving profitability within the competitive last-mile delivery market.

Palantir

Denver

Palantir Technologies develops data integration and analysis platforms leveraging artificial intelligence and machine learning. Their core products, including Foundry and Gotham, enable organizations to connect disparate data sources and operationalize insights through a central operating system. Palantir primarily serves government agencies and large enterprises requiring complex data analysis for operational decision-making and strategic planning, particularly in sectors like defense, finance, and healthcare.

Datadog

New York

Datadog delivers a comprehensive observability and analytics platform, providing cloud-scale monitoring of infrastructure, application performance (APM), log management, and security. Leveraging machine learning, Datadog’s products – including its anomaly detection features and Root Cause Analysis – proactively identify and resolve performance issues and security threats across complex cloud environments. Serving developers, IT operations, and business users, Datadog currently monitors over 760,000 customer hosts and processes over 150 billion metrics daily, establishing it as a leader in cloud observability.

Cloudflare

San Francisco

Cloudflare provides a comprehensive connectivity cloud platform delivering security, performance, and reliability for websites, applications, and APIs. Their core AI offering, Workers AI, enables developers to deploy and run machine learning models directly on Cloudflare’s globally distributed edge network. This uniquely positions Cloudflare to serve organizations requiring low-latency AI inference and robust protection against evolving cyber threats, particularly for AI-powered applications and workloads.

Robinhood

Menlo Park

Robinhood is a financial services company offering commission-free trading of stocks, options, and other financial instruments primarily to retail investors. They leverage AI-powered algorithms for trade execution, risk management, and to deliver personalized data and insights within their platform. Robinhood differentiates itself by providing accessible investing with fractional shares, extended trading hours, and cash management features, appealing to a new generation of investors.

Roblox AI

San Mateo

Roblox AI develops and deploys artificial intelligence solutions to power the Roblox platform, a user-generated massive multiplayer online game. Their core technology focuses on generative AI tools for content creation alongside AI-driven systems for content moderation and platform safety. Targeting the vast Roblox developer community and its millions of daily users, Roblox AI aims to scale content creation and maintain a safe, engaging virtual environment through automated solutions.

Expedia

Seattle

Expedia leverages artificial intelligence to optimize the travel booking process and enhance customer experience. Their core AI product is a recommendation engine and natural language processing (NLP) system powering personalized travel suggestions, dynamic pricing, and a conversational booking interface. Targeting leisure and business travelers, Expedia utilizes AI to increase booking conversion rates and customer loyalty through data-driven personalization at scale.

Symbotic

Wilmington

Symbotic develops end-to-end warehouse automation systems utilizing a fleet of fully autonomous robots and AI-powered software. Their technology orchestrates a high-density robotic system to improve efficiency, speed, and flexibility within warehouse operations. Symbotic targets large-scale consumer goods distributors and retailers seeking to address labor challenges, reduce operating costs, and optimize inventory management within increasingly complex supply chains.

Affirm

San Francisco

Affirm is a U.S.-based fintech company providing buy now, pay later (BNPL) solutions directly to consumers and through merchant partnerships. Their core technology utilizes machine learning models for real-time credit risk assessment and fraud detection, enabling flexible payment plans – including interest-free options and longer-term financing with transparent costs. Affirm differentiates itself by offering a BNPL option without late fees and providing upfront cost visibility, targeting consumers seeking accessible and predictable financing for purchases.

Zillow AI

Seattle

Zillow AI is a PropTech company operating the leading U.S. real estate marketplace. Their core technology is the Zestimate, an automated valuation model (AVM) leveraging machine learning to estimate property values, alongside AI-powered recommendation engines for listings. Zillow targets both home buyers/renters and real estate professionals, providing data-driven insights and a comprehensive platform for property search and valuation.

OpenAI

San Francisco

OpenAI is an AI research and deployment company whose stated mission is to ensure artificial general intelligence benefits all of humanity. It develops the GPT family of large language models and products including ChatGPT, the DALL-E and Sora generative models, and widely used developer APIs.

Cruise

San Francisco

Cruise developed autonomous-vehicle technology and operated a robotaxi service. In December 2024 majority owner GM ended funding for Cruise's robotaxi business and folded the team into GM to focus on driver-assistance and personal-vehicle autonomy; GM took full ownership in 2025.

Procore AI

Carpinteria

Procore Technologies provides a comprehensive construction management platform utilized throughout all phases of a project, from preconstruction to closeout. Their core innovation is Procore Helix, an AI-powered intelligence layer that leverages analytics and agentic workflows to automate tasks and deliver actionable insights. Procore targets general contractors and construction managers seeking to improve project efficiency, safety, and financial outcomes through data-driven decision-making.

Instacart

San Francisco

Instacart operates a North American e-commerce platform facilitating on-demand grocery delivery and pickup from over 300 retailers. Their core technology leverages AI-powered recommendation engines and search algorithms to personalize the shopping experience and optimize fulfillment. Instacart primarily serves individual consumers seeking convenience and rapid delivery of groceries and household essentials, while also offering services to retailers to enhance their online presence and delivery capabilities.

Stripe

San Francisco

Stripe AI provides financial infrastructure and APIs for online businesses, specializing in comprehensive payment processing and revenue management. Their core offering leverages AI to optimize payment authorization rates, detect and prevent fraud, and enable complex pricing models like usage-based billing. Stripe primarily serves internet-based businesses of all sizes seeking to improve revenue operations and expand into new markets through integrated, AI-driven financial tools.

SentinelOne

Mountain View

SentinelOne delivers a comprehensive cybersecurity platform, Singularity XDR, leveraging behavioral AI and machine learning to autonomously prevent, detect, and respond to threats across endpoints, cloud workloads, and identities. Their core innovation lies in Singularity Control Plane, a unified data lake and AI engine that enables real-time threat hunting, automated incident response, and proactive threat prevention without relying on signatures or cloud connectivity. Serving a diverse range of enterprise customers – including over 30% of the Fortune 500 – SentinelOne has been recognized as a leader in the Gartner Magic Quadrant for Endpoint Detection and Response and consistently demonstrates superior performance in independent testing like MITRE ATT&CK evaluations.

Unity AI

San Francisco

Unity AI develops AI tools integrated within the Unity real-time 3D development platform. Their core offerings include ML-Agents for training intelligent agents in simulation, Sentis for deploying AI models directly within applications, and Muse, an AI-powered assistant for content creation. While historically focused on gaming, Unity AI is expanding to serve developers across entertainment, automotive, architecture, and other industries requiring real-time 3D experiences with integrated AI functionality.

UiPath

New York

UiPath provides a platform for enterprise automation, combining Robotic Process Automation (RPA) with AI-powered agentic automation capabilities. Their core technology utilizes AI agents to automate complex, end-to-end business processes, extending beyond traditional task-based RPA. UiPath targets large organizations seeking to improve operational efficiency and accelerate AI transformation by freeing employees from repetitive tasks and enabling focus on higher-value work.

Cognex

Natick

Cognex Corporation develops and deploys machine vision systems and industrial barcode readers that automate manufacturing processes. Their core technology centers on deep learning-powered image analysis for quality inspection, defect detection, and robotic guidance. Cognex primarily serves the global manufacturing sector, offering solutions that improve production efficiency and reduce errors across industries like automotive, electronics, and food & beverage.

Anthropic

San Francisco

Anthropic is an AI safety and research company that builds Claude, a family of large language models focused on being reliable, interpretable, and steerable. Founded by former OpenAI researchers, it pioneered Constitutional AI and delivers Claude through consumer apps, a developer API, and major cloud partnerships.

Duolingo

Pittsburgh

Duolingo is a US-based EdTech company offering free, gamified language learning across a wide range of languages. Their core offering is enhanced by AI-powered personalization, most notably through Duolingo Max which integrates OpenAI’s GPT-4 to provide users with realistic conversation practice and detailed feedback. Targeting a broad consumer base of language learners, Duolingo differentiates itself through accessibility, a science-backed methodology, and increasingly sophisticated AI-driven features.

xAI

San Francisco

xAI is a US-based artificial intelligence company focused on developing and deploying large language models with a stated mission of advancing scientific discovery. Their primary product is Grok, a generative AI model accessible via API, web, and mobile platforms, offering enhanced speed, precision, and multilingual capabilities. xAI targets both individual users seeking an AI assistant and developers looking to integrate advanced LLM functionality into their applications, as demonstrated by their API offerings and recent partnership with the government of El Salvador.

Waymo

Mountain View

Waymo is an autonomous driving technology company developing self-driving vehicles. Operates robotaxi services in Phoenix and San Francisco.

ZoomInfo

Vancouver

ZoomInfo is a B2B data and intelligence platform that leverages AI to provide comprehensive company and contact information for sales, marketing, and recruiting professionals. Their core offering is a continuously updated database enriched with AI-driven insights into company firmographics, technologies used, and intent signals, enabling users to identify and prioritize in-market buyers. ZoomInfo primarily serves go-to-market teams seeking to improve lead generation, prospecting efficiency, and overall sales pipeline development.

Pega

Cambridge

Pega provides a low-code platform for business process and customer relationship management, enabling organizations to automate complex workflows and personalize customer interactions. Their core technology centers on AI-powered decisioning, allowing businesses to rapidly build and deploy applications without extensive coding. Pega targets large enterprises seeking to modernize legacy systems and improve operational agility through adaptable, AI-driven automation.

Aurora Innovation

Pittsburgh

Aurora Innovation develops the Aurora Driver, a full-stack self-driving system designed for long-haul trucking. Utilizing a combination of lidar, radar, and high-resolution cameras, coupled with their “Verifiable AI” safety framework, the Aurora Driver aims to enhance both the safety and efficiency of freight transportation. Currently, Aurora is operating autonomous trucks hauling customer loads in Texas and is focused on integrating its technology directly into existing freight operations to enable near 24/7 operation.

TripAdvisor

Needham

TripAdvisor operates a travel guidance platform leveraging natural language processing (NLP) to analyze user-generated reviews and extract insights about accommodations, restaurants, and attractions. Their core AI product is a sentiment analysis and topic modeling engine that powers personalized recommendations and facilitates comparative travel planning. Targeting leisure and business travelers, TripAdvisor differentiates itself by aggregating and structuring vast quantities of user reviews to provide data-driven decision-making support.

Databricks

San Francisco

Databricks provides a unified analytics platform for data engineering, data science, and machine learning. Known for Apache Spark and Delta Lake.

Upstart

San Mateo

Upstart leverages a proprietary AI-powered lending platform to originate personal loans and auto loans, partnering with banks and credit unions. Their core innovation lies in utilizing alternative data – beyond traditional credit scores – and machine learning models to assess borrower creditworthiness, resulting in lower loss rates and increased approval rates, particularly for underserved populations. Since its founding, Upstart has originated over $30 billion in loans and expanded its AI lending model to 72 partners, demonstrating significant traction within the financial services industry.

Magic Leap

Plantation

Magic Leap designs and manufactures spatial computing systems, most notably the Magic Leap 2 headset, which utilizes advanced waveguide technology for see-through augmented reality experiences. Their core innovation lies in developing and vertically integrating this custom silicon photonics and optics, enabling a wider field of view and improved image clarity compared to earlier AR headsets. Targeting enterprise clients in industries like healthcare, manufacturing, and remote assistance, Magic Leap aims to improve workflows and productivity through hands-free access to digital information and remote expert guidance.

C3.ai

Redwood City

C3.ai delivers a comprehensive Enterprise AI platform, including the C3 AI Suite, and a portfolio of over 130 pre-built, industry-specific AI applications focused on areas like predictive maintenance, fraud detection, and supply chain optimization. Their platform leverages capabilities in model development, deployment, and data integration, with a focus on large language models (LLMs) and generative AI to accelerate application development. C3.ai primarily serves large enterprises across sectors including manufacturing, financial services, oil & gas, and government, and has notably partnered with organizations like Baker Hughes and Schlumberger to deliver AI solutions for the energy industry.

Compass AI

New York

Compass AI is a technology-driven real estate brokerage leveraging AI-powered tools to optimize property transactions. Their core offering is a platform providing data-driven pricing recommendations and agent productivity features, alongside a “Concierge” service utilizing upfront investment in home preparation to accelerate sales. Compass targets both home sellers seeking premium results and real estate agents aiming to enhance client service and transaction efficiency.

Vicor

Andover

Vicor designs and manufactures modular power systems, specializing in high-density power conversion for demanding applications. Their core technology focuses on optimized 48V power delivery networks, crucial for efficient operation of AI data centers and GPU computing infrastructure. Vicor targets companies building high-performance computing systems, offering solutions that improve power efficiency and scalability in areas like AI, eMobility, and high-performance computing.

Anduril Industries

Costa Mesa

Anduril Industries develops autonomous defense systems for the U.S. and allied military forces. Their core offering is Lattice AI, an open software platform enabling sensor fusion, autonomous navigation, and command & control across multiple hardware platforms – including aerial, ground, and maritime systems. Anduril differentiates itself by applying Silicon Valley engineering principles to rapidly deliver adaptable, AI-powered capabilities traditionally reliant on lengthy defense procurement processes.

Cursor (Anysphere)

San Francisco

Cursor, built by Anysphere, is the leading AI-first code editor for pair programming with AI. Raised $2.3B in 2025 at a $29.3B valuation, becoming the fastest-growing dev tool.

Flexport

San Francisco

Flexport is a logistics platform that digitizes and streamlines global freight operations for businesses of all sizes. Utilizing a data-centric approach, Flexport provides SKU-level supply chain visibility and automation, encompassing ocean and air freight, customs brokerage, and container optimization. The company targets businesses seeking to improve efficiency, reduce costs, and gain real-time control over their end-to-end supply chains, from purchase order to final delivery.

Nuro

Mountain View

Nuro designs and manufactures fully autonomous, electric delivery vehicles – including the R2 and custom-built vehicles like those developed in collaboration with Uber and Lucid – focused on hyper-local goods transportation. Their core innovation is the Nuro Driver™ – an AI-first self-driving system prioritizing pedestrian safety and designed for commercial deployment, enabling scalable and responsible autonomy for partners. Nuro has secured key partnerships with major players like Uber, Kroger, and Domino’s, and recently received regulatory approval for commercial driverless delivery in multiple US states, demonstrating the maturity and viability of their technology.

Coursera

Mountain View

Coursera is an online learning platform offering university-level courses, specializations, and degrees from leading institutions and industry partners. Utilizing AI-powered recommendation systems and a generative AI assistant ("Coursera Coach"), the platform personalizes learning paths and provides on-demand support to students. Coursera primarily targets individuals seeking to upskill, reskill, or earn credentials for career advancement, with a focus on in-demand fields like machine learning and data science as evidenced by partnerships with companies like Google and IBM.

Lemonade AI

New York

Lemonade AI is a U.S.-based insurance company leveraging conversational AI chatbots – Maya for quoting and Jim for claims processing – to streamline the customer experience. Their technology enables instant quotes and rapid claims payouts, differentiating them from traditional insurers. Lemonade targets digitally-native consumers seeking a simplified and cost-effective insurance solution, as evidenced by high app store ratings and reported customer savings.

Thinking Machines Lab

San Francisco

Thinking Machines Lab, founded by former OpenAI CTO Mira Murati, builds more understandable and customizable AI systems. Raised a record $2B seed round.

Reflection AI

New York

Reflection AI is developing large language models focused on reasoning and long-context understanding, with a core product currently in limited access called “Reflect.” The company differentiates itself through a novel architecture designed to improve model reliability and reduce “hallucinations,” aiming for more trustworthy generative AI outputs. Backed by a $2 billion Series B led by Nvidia valuing the company at $8 billion, Reflection AI is positioning itself as a key player in the open intelligence movement, making its models accessible for research and development.

Commonwealth Fusion Systems

Cambridge

Commonwealth Fusion Systems is developing compact fusion power plants using high-temperature superconducting magnets. Spun out of MIT, they're building SPARC, the world's first net-energy fusion machine.

Wiz

New York

Wiz is a cloud security platform that provides vulnerability detection and security posture management for cloud environments. Utilizing a knowledge graph-based approach, Wiz maps cloud assets and identifies misconfigurations, vulnerabilities, and compliance risks across multi-cloud deployments. The platform targets security, development, and DevOps teams seeking to integrate security into the cloud development lifecycle and improve collaboration.

Lacework

San Jose

Lacework provides cloud security solutions utilizing behavioral analytics and machine learning to automate threat detection and response. Their Polygraph Data Platform continuously analyzes cloud workloads, network traffic, and identities to establish baseline behavior and identify anomalous activity indicative of security breaches or misconfigurations. Lacework targets cloud-native organizations seeking to reduce alert fatigue and improve security posture without relying solely on signature-based detection methods.

Navan

Palo Alto

Navan is a corporate travel and expense management platform utilizing AI-powered automation to streamline booking, reporting, and policy enforcement. Their core product integrates travel inventory from major suppliers with customizable spending controls and real-time data analysis to optimize travel spend. Navan targets mid-to-large sized businesses seeking to reduce costs and improve efficiency in their travel programs, offering both self-service and high-touch service options through their Navan Pro offering.

CoreWeave

Roseland

CoreWeave is a specialized GPU cloud provider that builds and operates Nvidia-based data centers and clusters for AI training and inference, serving major AI labs and enterprises. It IPO'd on Nasdaq on 28 March 2025 at $40/share (~$23B fully diluted valuation).

Ramp

New York

Ramp is a financial-technology company offering corporate cards and spend-management software that uses AI to automate expense categorization, bill payments, and savings recommendations. It is among the fastest-growing fintech startups in the US.

Inflection AI

Palo Alto

Inflection AI builds personal AI assistants and originally developed the Pi conversational assistant. In 2024 most of its team, including its co-founders, joined Microsoft, and the company refocused on enterprise AI products and models.

Crusoe

San Francisco

Crusoe builds renewable-powered, scalable AI infrastructure and cloud compute solutions. Their core offering centers around a proprietary inference engine, leveraging “MemoryAlloy” technology, designed to optimize performance for large-context AI workloads with low latency. Targeting enterprises deploying demanding AI applications, Crusoe provides both cloud-based services (Crusoe Cloud, Serverless Fine-Tuning, Managed Inference) and dedicated hardware to accelerate AI development and deployment.

Relativity Space

Long Beach

Relativity Space is an aerospace manufacturer utilizing large-scale 3D printing – specifically, their Stargate system – to build reusable rockets with significantly fewer parts than traditionally assembled vehicles. This additive manufacturing approach, coupled with high levels of automation, aims to reduce production costs and lead times for both launch services and advanced component manufacturing. Their target market includes commercial and government entities seeking more frequent and affordable access to space, as well as those requiring rapidly prototyped, complex metal components for aerospace and defense applications.

Tempus AI

Chicago

Tempus provides a platform combining comprehensive clinical and molecular data with artificial intelligence, primarily serving the oncology space. Their core offering is an operating system built upon the world’s largest library of such data, enhanced by recent advancements in generative AI like their clinical co-pilot, David, and digital pathology capabilities acquired through Paige. Tempus targets physicians, pharmaceutical companies, and patients seeking data-driven insights to improve cancer treatment decisions and accelerate drug development.

Rippling

San Francisco

Rippling provides a unified platform for managing core business functions including HR, IT, and finance. Their technology consolidates these traditionally disparate systems onto a single data platform, enabling automation and streamlined workflows. Rippling targets growing businesses seeking to improve operational efficiency and reduce administrative overhead by eliminating application switching and data silos.

Indigo Agriculture

Boston

Indigo Agriculture is an agricultural technology company focused on improving farm profitability and sustainability through a combination of biological seed treatments and data-driven regenerative agriculture programs. Their core technology utilizes naturally occurring microbes to enhance crop resilience and yield, coupled with a digital platform to measure and verify soil carbon sequestration for carbon credit generation. Indigo targets both farmers seeking increased productivity and corporations aiming to reduce Scope 3 emissions and meet sustainability goals through traceable, agriculture-based carbon offsets.

SambaNova Systems

Palo Alto

SambaNova Systems develops a full-stack AI platform, including DataScale processors (RDUs) and the Samba-1 model suite, designed to accelerate AI inference and fine-tuning. The company offers both cloud-based (SambaCloud) and on-premise (SambaStack) deployment options, targeting enterprises and governments with demanding data security and performance requirements. SambaNova positions itself as a high-performance, energy-efficient alternative to GPU-based AI infrastructure, particularly for large language models and sovereign AI initiatives.

Project44

Chicago

Project44 provides a decision intelligence platform, “Movement,” that leverages machine learning to deliver real-time supply chain visibility across all modes of transportation. The platform consolidates order, inventory, and shipment data – including IoT signals – to provide predictive insights and automate processes like freight procurement and disruption management. Project44 targets large shippers and logistics providers seeking to optimize costs, reduce risk, and improve service through data-driven supply chain control.

Blue Yonder

Scottsdale

Blue Yonder provides an end-to-end supply chain management platform leveraging AI and machine learning for planning, execution, commerce, and returns. Their core offering utilizes predictive analytics – generating millions of AI predictions daily – to optimize inventory, fulfillment, and overall supply chain performance. Blue Yonder targets large enterprises seeking to improve supply chain resilience, reduce costs, and enhance customer experiences through data-driven automation.

Pony.ai

Fremont

Pony.ai develops full-stack autonomous driving technology, focusing on Level 4 perception, localization, planning, and control systems. The company deploys this technology in both robotaxi and trucking applications, operating a fleet for public and commercial use. Pony.ai targets the deployment of autonomous vehicles as a mobility service and freight solution in major urban centers and logistics hubs.

Netskope

Santa Clara

Netskope provides cloud-native security and networking solutions focused on securing data and applications across cloud environments, SaaS, and increasingly, generative AI. Their core technology is a context-aware Zero Trust Engine that analyzes user and entity activity to prevent data loss and mitigate threats. Netskope targets enterprises seeking to consolidate security and networking infrastructure into a single platform for improved visibility, reduced complexity, and consistent policy enforcement across all digital channels.

Fireblocks

New York

Fireblocks provides a platform for the secure custody, transfer, and settlement of digital assets for financial institutions and fintech companies. Their core technology is a multi-layer, AI-powered security infrastructure that mitigates risks associated with blockchain transactions and wallet management. Fireblocks targets businesses requiring scalable and compliant digital asset operations, offering solutions ranging from treasury management to embedded crypto wallets for consumer applications.

DataRobot

Boston

DataRobot offers a unified AI platform focused on enabling enterprises to build, deploy, and manage “agentic AI” applications – autonomous AI agents designed to handle complex tasks. Their platform differentiates itself through a focus on the full agent lifecycle, offering customizable blueprints and integrations to accelerate development and deployment across various enterprise teams. DataRobot positions itself as a leader in moving beyond pilot projects, aiming to deliver measurable business outcomes with AI, and currently supports applications like automated customer service and intelligent document processing.

Snyk

Boston

Snyk provides a developer security platform focused on securing modern applications, particularly those leveraging AI. Their core technology, DeepCode AI, utilizes machine learning models trained on security data to power static analysis, software composition analysis, and container/Kubernetes security testing throughout the software development lifecycle. Snyk targets organizations building and deploying applications – especially AI-native ones – seeking to proactively identify and remediate vulnerabilities with automated, AI-driven workflows.

Xaira Therapeutics

San Francisco

Xaira Therapeutics is building a generative AI platform focused on de novo protein design and drug candidate creation, leveraging advancements from the technology behind AlphaFold. The company’s core innovation lies in applying AI to not just predict protein structures, but to generate novel protein therapeutics with optimized properties for a range of diseases. Backed by a $1 billion Series A funding round, Xaira Therapeutics aims to accelerate drug discovery beyond traditional methods and is initially focusing on developing therapeutics for currently undruggable targets.

KoBold Metals

Berkeley

KoBold Metals combines machine learning and scientific computing with human geological expertise to discover deposits of critical minerals such as copper, cobalt, nickel and lithium for the clean-energy transition. Backed by Bill Gates and Jeff Bezos, it has raised about $1 billion and is developing the large Mingomba copper deposit in Zambia.

Lime

San Francisco

Lime is a micromobility provider operating fleets of shared electric scooters. The company leverages proprietary AI-powered demand prediction and route optimization algorithms to dynamically balance scooter availability and proactively redistribute inventory across its operating areas. This technology enables Lime to maximize scooter utilization, minimize rider wait times, and improve operational efficiency in dense urban environments.

Sila Nanotechnologies

Alameda

Sila Nanotechnologies develops and manufactures silicon anode materials that significantly increase the energy density and performance of lithium-ion batteries. Their core product, Titan Silicon, is a drop-in replacement for traditional graphite anodes, delivering up to 20% more energy density and faster charging capabilities. Sila targets battery manufacturers and device companies across electric vehicle, consumer electronics, and industrial sectors, offering both materials supply and battery engineering services to optimize cell performance.

Form Energy

Somerville

Form Energy develops iron-air batteries for multi-day energy storage. Their technology enables utilities to store renewable energy for 100+ hours at a fraction of lithium-ion costs.

OneTrust

Atlanta

OneTrust provides a unified platform for privacy, security, and governance automation, enabling organizations to manage data and comply with evolving regulations. Their core offering centers on AI governance solutions that embed compliance controls throughout the entire AI lifecycle, from data collection to deployment. OneTrust targets enterprises seeking to operationalize responsible AI practices and mitigate risk while accelerating innovation, particularly those facing complex regulatory landscapes.

Tanium

Kirkland

Tanium provides a real-time platform that unifies endpoint data to deliver autonomous IT and security solutions. Their core technology leverages AI and machine learning to proactively identify and remediate threats and operational issues across complex IT environments. Tanium targets large, security-conscious organizations requiring comprehensive endpoint visibility and control to mitigate risk and maintain operational resilience.

Shield AI

San Diego

Shield AI develops AI-powered autonomous systems for defense applications, specializing in software that enables unmanned aerial vehicles to operate effectively in communication-denied environments. Their core product, Hivemind, is an AI pilot capable of independently executing complex flight plans and tactical maneuvers on platforms like the MQ-20 Avenger and Kratos’ MQM-178 Firejet. Shield AI targets the defense and security sectors by providing resilient, fully-autonomous capabilities that reduce operator workload and enhance mission success in contested environments.

Freenome

South San Francisco

Freenome develops a blood-based, multiomics screening platform designed for early cancer detection, utilizing both genomic and proteomic biomarkers. Their core technology employs machine learning algorithms to analyze complex patterns in blood samples, aiming to detect cancer signals prior to symptom onset and improve screening accessibility. Currently focused on colorectal cancer with their CRC-DETECT test, Freenome is conducting clinical trials to validate performance and expand their platform to detect multiple cancer types, with a goal of increasing survival rates through earlier diagnosis.

Cybereason

Boston

Cybereason is a U.S.-based cybersecurity company specializing in Extended Detection and Response (XDR). Their platform utilizes AI and machine learning to analyze petabytes of data across the entire IT environment, providing automated threat prediction and response with minimal human intervention. Cybereason targets enterprises seeking a comprehensive, AI-driven security solution validated by MITRE to improve detection rates and accelerate remediation times.

Automation Anywhere

San Jose

Automation Anywhere delivers agentic process automation software for large enterprises, combining robotic process automation (RPA) with artificial intelligence. Their platform utilizes AI to enable automation bots to independently discover, adapt to, and execute end-to-end business processes with minimal human intervention. Targeting industries like healthcare, financial services, and manufacturing, Automation Anywhere aims to improve operational agility and accelerate automation scalability for mission-critical tasks.

Crusoe Energy

Denver

Crusoe Energy provides scalable AI infrastructure and cloud compute services, specializing in deployments for large-context AI models. Their core offering, Crusoe Cloud, leverages proprietary MemoryAlloy technology and optimized hardware – including the latest NVIDIA & AMD GPUs – to deliver accelerated inference speeds and reduced costs. Crusoe targets organizations requiring high-performance, reliable AI compute, uniquely powered by stranded natural gas and renewable energy sources to offer a sustainable infrastructure solution.

Niantic

San Francisco

Niantic develops augmented reality (AR) applications that overlay digital experiences onto the physical world. Their core technology leverages spatial mapping and AR to create location-based games and experiences, most notably demonstrated by the globally successful Pokémon GO. Niantic targets mobile gamers and aims to foster real-world exploration and community building through interactive AR experiences.

Figure AI

Sunnyvale

Figure AI is developing a general-purpose humanoid robot, Figure 03, designed to perform everyday tasks in home and eventually industrial settings. The company’s core innovation lies in its AI agent, Helix, which enables the robot to understand and navigate dynamic, real-world environments – a key challenge in robotics. Currently focused on demonstrating in-home capabilities, Figure recently announced a collaboration with BMW to explore deployment of their robots in manufacturing facilities, signaling a move towards broader industrial applications.

Insitro

South San Francisco

Insitro leverages high-throughput phenotypic screening and machine learning to build predictive models of human biology, focusing initially on diseases like NASH and heart failure. Their platform combines large-scale experimental data – including cellular assays and human genetic data – with proprietary machine learning algorithms to identify and validate drug targets and predict clinical trial success. Notably, Insitro has established collaborations with pharmaceutical companies like Bristol Myers Squibb and Roche to apply their technology to specific disease areas and advance novel therapeutics.

Socure

New York

Socure provides AI-powered identity verification and fraud prevention solutions for financial institutions and online businesses. Their core technology leverages a dynamic, 360-degree view of identity built on analysis of billions of real-world transactions to deliver accurate, real-time risk assessment. This enables clients to streamline customer onboarding, reduce fraud losses, and increase acceptance rates across 190+ countries without requiring code changes.

Plaid

San Francisco

Plaid provides APIs that connect consumer bank accounts to fintech applications, powering payments, lending, and personal-finance tools. It applies machine learning to financial data for fraud detection and identity verification.

Fivetran

Oakland

Fivetran is a data integration platform that automates the movement of data from over 700 sources – including SaaS applications, databases, and files – into cloud data warehouses and lakes. Their fully-managed pipelines eliminate the need for custom ETL code, enabling businesses to consolidate data for analytics and AI initiatives. Fivetran primarily serves organizations requiring reliable, scalable data integration to power business intelligence, data science workflows, and cloud migrations.

Cerebras Systems

Sunnyvale

Cerebras Systems develops AI hardware, specifically the Wafer Scale Engine, a large-scale chip designed to accelerate deep learning workloads. Unlike traditional GPUs, Cerebras’ technology aims to significantly reduce the time and cost associated with training complex AI models. Their target market is organizations requiring high-performance computing for demanding AI applications, such as large language models and scientific computing.

Boom Supersonic

Denver

Boom Supersonic is developing Overture, a next-generation supersonic airliner, and leverages AI extensively throughout its design and operational systems. Their technology focuses on aerodynamic optimization via AI-driven simulations, and the development of autonomous systems for flight control and performance enhancement – building on learnings from the XB-1 demonstrator aircraft. With confirmed orders from major airlines including United, American, and Japan Airlines, Boom aims to revitalize commercial supersonic travel with a focus on speed and efficiency.

Collective Health

San Francisco

Collective Health is a technology-enabled third-party administrator (TPA) that integrates and optimizes employee health benefits administration for self-funded employers. Their platform utilizes data analytics and AI-driven personalization to connect medical, pharmacy, and ancillary benefits into a single, user-friendly experience. This solution aims to reduce administrative costs and improve member engagement by providing a simplified and connected benefits journey for employers and their employees.

Thumbtack

San Francisco

Thumbtack operates a digital marketplace connecting homeowners with local professionals for a wide range of home services. Their core technology utilizes AI-powered matching algorithms to connect customers with pros based on project needs, location, and verified qualifications. This targeted approach differentiates Thumbtack by streamlining the often-complex process of finding and vetting reliable home service providers for US consumers.

Deel

San Francisco

Deel is a global payroll and compliance platform that simplifies international workforce management for businesses of all sizes. Their core technology utilizes AI-driven automation to calculate local payroll taxes, ensure regulatory compliance across 150+ countries, and streamline HR processes for both employees and contractors. Deel primarily serves companies seeking to rapidly expand their international presence without the complexities of establishing foreign entities or managing diverse compliance requirements.

ThoughtSpot

Sunnyvale

ThoughtSpot provides an agentic analytics platform that enables users to access and analyze live data through natural language queries. Their core technology utilizes AI agents to automate the analytics workflow, surfacing insights and delivering answers directly within existing business applications like Salesforce and ServiceNow. ThoughtSpot targets data analysts, engineers, and business users across enterprises seeking to move beyond traditional BI with self-service analytics and automated insight delivery.

Zipline

South San Francisco

Zipline Rwanda operates an autonomous drone delivery service focused on rapidly distributing critical medical supplies, including blood and vaccines, to remote and underserved healthcare facilities. Their core technology is a fully integrated platform encompassing drone aircraft, automated logistics software, and a proprietary demand forecasting system to optimize inventory and delivery routes. Targeting the healthcare sector and governments in regions with challenging infrastructure, Zipline provides instant, reliable access to essential medical products, reducing delivery times and improving health outcomes.

AlphaSense

New York

AlphaSense is a market-intelligence platform that uses AI and natural-language search to surface insights from filings, transcripts, news, and research. It serves financial firms and corporations and acquired research provider Tegus in 2024.

Highspot

Seattle

Highspot is a sales enablement platform that utilizes AI to improve go-to-market team performance. Their core technology, Nexus™, analyzes sales interactions – including spoken communication, content shared, and buyer engagement – to provide data-driven insights and automated coaching. Highspot targets large enterprises seeking to enhance sales skills, optimize content utilization, and drive revenue through AI-powered enablement solutions integrated directly into the sales workflow.

Plus.ai

Cupertino

Plus.ai develops autonomous driving technology specifically for long-haul freight trucking. Their core product, SuperDrive, is an AI-powered autonomous system utilizing large AI models and generative AI to enable Level 4 autonomy on commercial vehicles. Targeting partnerships with major truck manufacturers like TRATON, Hyundai, and IVECO, as well as fleets like Amazon and DSV, Plus.ai aims to deliver scalable, factory-built autonomous trucking solutions to improve safety and efficiency in the logistics industry.

Chainguard

Kirkland

Chainguard is a software-supply-chain security company that provides hardened, minimal-vulnerability container images to reduce risk and meet compliance requirements, including for AI and ML workloads. Its catalog has grown to over 1,400 images used by 100+ enterprises. It raised a $356M Series D in 2025 at a $3.5B valuation, with about $612M raised in total.

Scale AI

San Francisco

ScaleAI provides data labeling and annotation services critical for developing and deploying machine learning models. Their core offering is a managed data platform utilizing human-in-the-loop workflows and proprietary technology to deliver high-quality training data at scale. ScaleAI primarily serves companies operating in data-intensive AI applications like autonomous vehicles, geospatial intelligence, and robotics, accelerating their model development lifecycles.

Butterfly Network

Burlington

Butterfly Network develops handheld, whole-body ultrasound devices integrated with AI-powered software for point-of-care imaging. Their flagship product, the Butterfly iQ3, utilizes a single probe to deliver diagnostic imaging across a wide range of clinical applications. Butterfly Network serves diverse markets including individual medical practices, large healthcare systems, and medical education programs, offering a portable and accessible alternative to traditional ultrasound technology.

Veev

Hayward

Veev is a U.S.-based construction technology company utilizing AI-powered design and automated manufacturing to produce modular homes. Their core technology integrates digital modeling with robotic assembly lines to streamline construction and improve precision. Targeting the residential housing market – and backed by Lennar – Veev aims to deliver homes with increased speed, quality, and potentially lower costs compared to traditional building methods.

Gong

San Francisco

Gong is a US-based revenue intelligence platform that utilizes multimodal AI – analyzing call recordings, emails, and meeting transcripts – to provide insights into sales conversations. Their platform offers specialized AI agents and applications designed to improve sales team performance, forecast accuracy, and overall revenue outcomes. Gong primarily targets go-to-market teams within larger organizations seeking data-driven improvements to sales effectiveness and pipeline management.

Vercel

San Francisco

Vercel is a frontend cloud platform providing developers with the infrastructure to build and deploy web applications. Their core offering is an AI Cloud, integrating AI SDKs and edge functions to enable personalized and dynamic web experiences. Vercel targets web developers seeking to leverage AI capabilities directly within their frontend applications, focusing on performance and scalability.

Checkr

San Francisco

Checkr is a US-based technology company that streamlines the employee background check process for enterprises. Their platform utilizes AI-powered automation to deliver faster, more accurate reports with standardized data and customizable filtering options. This enables companies to accelerate hiring, reduce candidate drop-off, and mitigate risk associated with background screening compliance.

Illumio

Sunnyvale

Illumio provides breach containment platforms for organizations operating in hybrid and multi-cloud environments. Their core technology is an AI-powered security graph that maps application dependencies to identify and contain lateral threat movement. Illumio targets enterprises seeking to improve their Zero Trust security posture and minimize the impact of breaches through proactive, application-centric microsegmentation.

Verbit

New York

Verbit is a US-based AI company specializing in highly accurate transcription and captioning services. Their core technology, the Captivate™ ASR engine and enhanced by Gen.V™ generative AI, delivers rapid, customizable transcripts with automated summarization and keyword extraction. Verbit primarily serves speech-intensive industries like legal and education, offering solutions to improve accessibility, enhance productivity, and derive actionable insights from audio and video content.

ClickUp

San Diego

ClickUp is a comprehensive productivity platform consolidating tasks, documents, goals, and communication into a single workspace. Their core offering leverages a proprietary AI assistant integrated directly within the platform to minimize context switching and enhance both human and AI workflow efficiency. Targeting teams and organizations seeking to consolidate software and improve overall productivity, ClickUp aims to reduce wasted effort by centralizing work and knowledge.

Mapbox

San Francisco

Mapbox provides location-based APIs and SDKs that enable developers to integrate customizable mapping, navigation, and search functionality into applications across web, mobile, and automotive platforms. Their core technology centers on a geospatial data platform and AI-powered routing engines that deliver real-time traffic insights and precise location data. Mapbox serves businesses requiring advanced location services, including logistics, ride-sharing, automotive manufacturers, and weather data providers, offering scalable solutions built on data from over half a billion monthly active users.

Forter

New York

Forter provides AI-powered fraud prevention solutions for online retailers and marketplaces. Their core technology, Identity Intelligence, analyzes user behavior and transaction data to accurately identify and block fraudulent activity while minimizing false positives. This enables merchants to increase approval rates for legitimate customers and reduce chargebacks, ultimately improving revenue and customer experience.

Melio

New York

Melio is a B2B payment platform that streamlines accounts payable and receivable for small and medium-sized businesses. Utilizing automated invoice processing and payment workflows, Melio facilitates digital payments between businesses and their vendors, integrating with accounting software like QuickBooks and Xero. The platform targets businesses seeking to optimize cash flow and reduce manual AP/AR processes without disrupting existing vendor payment preferences.

Axiom Space

Houston

Axiom Space is a leading provider of human spaceflight services and developer of next-generation space infrastructure, including the future Axiom Station. The company utilizes AI-powered autonomous systems for spacecraft operation and is currently focused on enabling commercial access to low-Earth orbit and beyond via end-to-end mission services. Axiom Space targets both private astronauts and national space agencies, offering a platform for research, in-space manufacturing, and the advancement of space-based technologies.